Europe active pharmaceutical ingredients market was valued at $49.52 billion in 2021 and will grow by 7.3% annually over 2021-2028, driven by rising adoption of biologics in disease management, increasing regulatory approvals, patent expiration of major drugs, growing trend of outsourcing and increase in geriatric population.
Highlighted with 95 tables and 69 figures, this 193-page report “Europe Active Pharmaceutical Ingredients (API) Market 2021-2028 by Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Country: Trend Forecast and Growth Opportunity” is based on a comprehensive research of the entire Europe active pharmaceutical ingredients market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2018-2021 and provides forecast from 2022 till 2028 with 2021 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)
In-depth qualitative analyses include identification and investigation of the following aspects:
• Market Structure
• Growth Drivers
• Restraints and Challenges
• Emerging Product Trends & Market Opportunities
• Porter’s Fiver Forces
The trend and outlook of Europe market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19. The balanced (most likely) projection is used to quantify Europe active pharmaceutical ingredients market in every aspect of the classification from perspectives of Synthesis, Manufacturing Process, Therapeutic Application, Drug Type, and Country.
Based on Synthesis, the Europe market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
Synthetic API
• Branded Synthetic API
• Generic Synthetic API
Biotech API by Drug Type:
• Monoclonal Antibodies
• Recombinant Proteins
• Vaccines
• Other Biotech APIs
Biotech API by Customer Base:
• Innovative Biologic API
• Generic Biosimilar API
Biotech API by Expression Technology:
• Mammalian Expression
• Microbial Expression
• Yeast Expression
• Insect Expression
• Other Expression Technologies
HPAPI
• Branded HPAPI
• Generic HPAPI
Based on Manufacturing Process, the Europe market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
Captive Manufacturing
• Branded Captive API
• Generic Captive API
Merchant Manufacturing by Drug Type:
• Branded Merchant API
• Generic Merchant API
Merchant Manufacturing by Drug Synthesis:
• Merchant Synthetic API
• Merchant Biotech API
By Drug Type, the Europe market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
• Branded Prescription Drugs
• Generic Prescription Drugs
• OTC Drugs
Geographically, the following national/local markets are fully investigated:
• Germany
• UK
• France
• Spain
• Italy
• Russia
• Rest of Europe (further segmented into Netherlands, Switzerland, Poland, Sweden, Belgium, Austria, Ireland, Norway, Denmark, and Finland)
For each key country, detailed analysis, and data for annual revenue ($ bn) are available for 2018-2028. The breakdown of key national markets by Synthesis, Manufacturing Process, and Therapeutic Application over the forecast years are also included.
The report also covers current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.
Selected Key Players:
AbbVie Inc.
Astrazeneca
Aurobindo Pharma Ltd.
BASF
Bayer AG
Boehringer Ingelheim
Catalent Inc.
Dr. Reddy's Laboratories
F. Hoffmann-La Roche
GlaxoSmithKline plc
Lonza Group
Lupin Limited
Merck & Co., Inc.
Mylan NV
Novartis International AG
Pfizer Inc.
Sanofi
Sun Pharmaceutical Industries Ltd.
Teva Pharmaceutical Industries Ltd.
Thermo Fisher Scientific
(Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)
1 Introduction 9
1.1 Industry Definition and Research Scope 9
1.1.1 Industry Definition 9
1.1.2 Research Scope 10
1.2 Research Methodology 13
1.2.1 Overview of Market Research Methodology 13
1.2.2 Market Assumption 14
1.2.3 Secondary Data 14
1.2.4 Primary Data 14
1.2.5 Data Filtration and Model Design 15
1.2.6 Market Size/Share Estimation 16
1.2.7 Research Limitations 17
1.3 Executive Summary 18
2 Market Overview and Dynamics 21
2.1 Market Size and Forecast 21
2.1.1 Impact of COVID-19 on World Economy 22
2.1.2 Impact of COVID-19 on the Market 24
2.2 Major Growth Drivers 31
2.3 Market Restraints and Challenges 39
2.4 Emerging Opportunities and Market Trends 42
2.5 Porter’s Fiver Forces Analysis 46
3 Segmentation of Europe Market by Synthesis 50
3.1 Market Overview by Synthesis 50
3.2 Synthetic API 52
3.2.1 Branded Synthetic API 53
3.2.2 Generic Synthetic API 54
3.3 Biotech API 55
3.3.1 Biotech API by Drug Type 56
3.3.1.1 Monoclonal Antibodies 57
3.3.1.2 Recombinant Proteins 58
3.3.1.3 Vaccines 59
3.3.1.4 Other Biotech APIs 60
3.3.2 Biotech API by Category 61
3.3.2.1 Innovative Biologic API 62
3.3.2.2 Generic Biosimilar API 63
3.3.3 Biotech API by Expression Technology 64
3.3.3.1 Mammalian Expression 65
3.3.3.2 Microbial Expression 66
3.3.3.3 Yeast Expression 67
3.3.3.4 Insect Expression 68
3.3.3.5 Other Expression Technologies 69
3.4 HPAPI 70
3.4.1 Branded HPAPI 71
3.4.2 Generic HPAPI 72
4 Segmentation of Europe Market by Manufacturing Process 73
4.1 Market Overview by Manufacturing Process 73
4.2 Captive Manufacturing 75
4.2.1 Branded Captive API 76
4.2.2 Generic Captive API 77
4.3 Merchant Manufacturing 78
4.3.1 Merchant Manufacturing by Drug Type 79
4.3.1.1 Branded Merchant API 80
4.3.1.2 Generic Merchant API 81
4.3.2 Merchant Manufacturing by Drug Synthesis 82
4.3.2.1 Merchant Synthetic API 83
4.3.2.2 Merchant Biotech API 84
5 Segmentation of Europe Market by Therapeutic Application 85
5.1 Market Overview by Therapeutic Application 85
5.2 Infectious Diseases 87
5.3 Oncology 88
5.4 Ophthalmology 89
5.5 Cardiovascular Disorders 90
5.6 Central Nervous System 91
5.7 Pulmonary Disorders 92
5.8 Orthopedics 93
5.9 Other Applications 94
6 Segmentation of Europe Market by Drug Type 95
6.1 Market Overview by Drug Type 95
6.2 Branded Prescription Drugs 97
6.3 Generic Prescription Drugs 98
6.4 OTC Drugs 99
7 European Market 2021-2028 by Country 100
7.1 Overview of European Market 100
7.2 UK 103
7.3 France 105
7.4 Germany 107
7.5 Spain 109
7.6 Italy 111
7.7 Russia 113
7.8 Rest of European Market 115
8 Competitive Landscape 117
8.1 Overview of Key Vendors 117
8.2 New Product Launch, Partnership, Investment, and M&A 120
8.3 Company Profiles 121
AbbVie Inc. 121
Astrazeneca 123
Aurobindo Pharma Ltd. 128
BASF 131
Bayer AG 134
Boehringer Ingelheim 138
Catalent Inc. 143
Dr. Reddy's Laboratories 146
F. Hoffmann-La Roche 148
GlaxoSmithKline plc 150
Lonza Group 155
Lupin Limited 160
Merck & Co., Inc. 163
Mylan NV 166
Novartis International AG 169
Pfizer Inc. 172
Sanofi 177
Sun Pharmaceutical Industries Ltd. 180
Teva Pharmaceutical Industries Ltd. 183
Thermo Fisher Scientific 185
9 Investing in Europe Market: Risk Assessment and Management 187
9.1 Risk Evaluation of Europe Market 187
9.2 Critical Success Factors (CSFs) 190
Related Reports and Products 193
List of Tables:
Table 1. Snapshot of Europe Active Pharmaceutical Ingredients (API) Market in Balanced Perspective, 2021-2028 19
Table 2. World Economic Outlook, 2021-2031 23
Table 3. World Top 10 Pharmaceutical Companies Based on Projected R&D Spending in 2026, $ bn 38
Table 4. Main Product Trends and Market Opportunities in Europe Active Pharmaceutical Ingredients (API) Market 42
Table 5. Europe Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 50
Table 6. Europe Active Pharmaceutical Ingredients (API) Market: Synthetic API by Drug Type, 2018-2028, $ bn 52
Table 7. Europe Active Pharmaceutical Ingredients (API) Market: Biotech API by Drug Type, 2018-2028, $ bn 56
Table 8. Europe Active Pharmaceutical Ingredients (API) Market: Biotech API by Category, 2018-2028, $ bn 61
Table 9. Europe Active Pharmaceutical Ingredients (API) Market: Biotech API by Expression Technology, 2018-2028, $ bn 64
Table 10. Europe Active Pharmaceutical Ingredients (API) Market: HPAPI by Drug Type, 2018-2028, $ bn 70
Table 11. Europe Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 73
Table 12. Europe Active Pharmaceutical Ingredients (API) Market: Captive Manufacturing by Drug Type, 2018-2028, $ bn 75
Table 13. Europe Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Type, 2018-2028, $ bn 79
Table 14. Europe Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Synthesis, 2018-2028, $ bn 82
Table 15. Europe Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 85
Table 16. Europe Active Pharmaceutical Ingredients (API) Market by Drug Type, 2018-2028, $ bn 95
Table 17. Europe Active Pharmaceutical Ingredients (API) Market by Country, 2018-2028, $ bn 102
Table 18. UK Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 104
Table 19. UK Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 104
Table 20. UK Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 104
Table 21. France Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 106
Table 22. France Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 106
Table 23. France Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 106
Table 24. Germany Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 108
Table 25. Germany Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 108
Table 26. Germany Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 108
Table 27. Spain Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 110
Table 28. Spain Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 110
Table 29. Spain Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 110
Table 30. Italy Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 112
Table 31. Italy Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 112
Table 32. Italy Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 112
Table 33. Russia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 114
Table 34. Russia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 114
Table 35. Russia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 114
Table 36. Active Pharmaceutical Ingredients (API) Market in Rest of Europe by Country, 2018-2028, $ bn 116
Table 37. AbbVie Inc.: Company Snapshot 121
Table 38. AbbVie Inc.: Product Portfolio 121
Table 39. AbbVie Inc.: Revenue, 2018-2020, $ bn 122
Table 40. Astrazeneca: Company Snapshot 123
Table 41. Astrazeneca: Revenue, 2018-2020, $ bn 124
Table 42. Aurobindo Pharma Ltd.: Company Snapshot 128
Table 43. Aurobindo Pharma Ltd.: Product Portfolio 129
Table 44. BASF: Company Snapshot 131
Table 45. BASF: Business Segmentation 132
Table 46. BASF: Revenue by Region 132
Table 47. Bayer AG: Company Snapshot 134
Table 48. Bayer AG: Business Segmentation 135
Table 49. Bayer AG: Revenue, 2018-2020, € bn 135
Table 50. Boehringer Ingelheim: Company Snapshot 138
Table 51. Boehringer Ingelheim: Business Segmentation in 2019 139
Table 52. Boehringer Ingelheim: Product Portfolio 139
Table 53. Boehringer Ingelheim: Revenue, 2018-2020, EUR billion 140
Table 54. Boehringer Ingelheim: Revenue by Region in 2019 140
Table 55. Catalent Inc.: Company Snapshot 143
Table 56. Catalent Inc.: Business Segmentation in 2018 144
Table 57. Catalent Inc.: Product Portfolio 144
Table 58. Catalent Inc.: Revenue, 2018-2020, $ million 145
Table 59. Catalent Inc.: Revenue by Region in 2018 145
Table 60. Dr. Reddy's Laboratories: Company Snapshot 146
Table 61. Dr. Reddy's Laboratories: Business Segmentation 146
Table 62. Dr. Reddy's Laboratories: Revenue, 2019-2021, $ bn 147
Table 63. F. Hoffmann-La Roche: Company Snapshot 148
Table 64. F. Hoffmann-La Roche: Business Segmentation 149
Table 65. GlaxoSmithKline: Company Snapshot 150
Table 66. GlaxoSmithKline: Business Segmentation 151
Table 67. GlaxoSmithKline: Product Portfolio 152
Table 68. GlaxoSmithKline: Revenue, 2018-2020, $ bn 153
Table 69. Lonza Group: Company Snapshot 155
Table 70. Lonza Group: Business Segmentation in 2018 156
Table 71. Lonza Group: Product Portfolio 156
Table 72. Lonza Group: Revenue by Region in 2018 157
Table 73. Lupin Limited: Company Snapshot 160
Table 74. Lupin Limited: Business Segmentation 160
Table 75. Merck & Co., Inc.: Company Snapshot 163
Table 76. Merck & Co., Inc.: Business Segmentation 163
Table 77. Merck & Co., Inc.: Revenue, 2018-2020, $ bn 164
Table 78. Mylan NV: Company Snapshot 166
Table 79. Mylan NV: Revenue, 2017-2019, $ bn 167
Table 80. Novartis International AG: Company Snapshot 169
Table 81. Novartis International AG: Business Segmentation 169
Table 82. Novartis International AG: Revenue, 2017-2019, $ bn 170
Table 83. Pfizer Inc.: Company Snapshot 172
Table 84. Pfizer Inc.: Business Segmentation 173
Table 85. Pfizer Inc.: Product Portfolio 174
Table 86. Pfizer Inc.: Revenue, 2018-2020, $ bn 174
Table 87. Sanofi: Company Snapshot 177
Table 88. Sanofi: Business Segmentation 177
Table 89. Sanofi: Revenue, 2018-2020, $ bn 178
Table 90. Sun Pharmaceutical Industries Limited: Company Snapshot 180
Table 91. Teva Pharmaceutical Industries Ltd.: Company Snapshot 183
Table 92. Teva Pharmaceutical Industries Ltd.: Business Segmentation 184
Table 93. Thermo Fisher Scientific: Company Snapshot 185
Table 94. Risk Evaluation for Investing in Europe Market, 2021-2028 188
Table 95. Critical Success Factors and Key Takeaways 191
