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Global Active Pharmaceutical Ingredients API Market


Global Active Pharmaceutical Ingredients (API) Market 2020-2026 by Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Region: Trend Forecast and Growth Opportunity

Report code: SDMRHE1298203 | Industry: Healthcare and Social Assistance | Published On: 44008


Global active pharmaceutical ingredients (API) market will reach $293.5 billion by 2026, growing by 7.2% annually over 2020-2026 owing to the rising need for medicine and pharmaceutical agents amid the COVID-19 pandemic.
Highlighted with 91 tables and 99 figures, this 190-page report “Global Active Pharmaceutical Ingredients (API) Market 2020-2026 by Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Region: Trend Forecast and Growth Opportunity” is based on a comprehensive research of the entire global API market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2015-2019 and provides forecast from 2020 till 2026 with 2019 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)
In-depth qualitative analyses include identification and investigation of the following aspects:
• Market Structure
• Growth Drivers
• Restraints and Challenges
• Emerging Product Trends & Market Opportunities
• Porter’s Fiver Forces
The trend and outlook of global market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19. The balanced (most likely) projection is used to quantify global API market in every aspect of the classification from perspectives of Synthesis, Manufacturing Process, Therapeutic Application, Drug Type, and Region.

Based on Synthesis, the global market is segmented into the following sub-markets with annual revenue for 2015-2026 included in each section.
Synthetic API
• Branded Synthetic API
• Generic Synthetic API
Biotech API by Drug Type:
• Monoclonal Antibodies
• Recombinant Proteins
• Vaccines
• Other Biotech APIs
Biotech API by Customer Base:
• Innovative Biologic API
• Generic Biosimilar API
Biotech API by Expression Technology:
• Mammalian Expression
• Microbial Expression
• Yeast Expression
• Insect Expression
• Other Expression Technologies
HPAPI
• Branded HPAPI
• Generic HPAPI

Based on Manufacturing Process, the global market is segmented into the following sub-markets with annual revenue for 2015-2026 included in each section.
Captive Manufacturing
• Branded Captive API
• Generic Captive API
Merchant Manufacturing by Drug Type:
• Branded Merchant API
• Generic Merchant API
Merchant Manufacturing by Drug Synthesis:
• Merchant Synthetic API
• Merchant Biotech API

Based on Therapeutic Application, the global market is segmented into the following sub-markets with annual revenue for 2015-2026 included in each section.
• Infectious Diseases
• Oncology
• Ophthalmology
• Cardiovascular Disorders
• Central Nervous System
• Pulmonary Disorders
• Orthopedics
• Other Applications

Based on Drug Type, the global market is segmented into the following sub-markets with annual revenue for 2015-2026 included in each section.
• Branded Prescription Drugs
• Generic Prescription Drugs
• OTC Drugs

Geographically, the following regions together with the listed national/local markets are fully investigated:
• APAC (Japan, China, South Korea, Australia, India, and Rest of APAC; Rest of APAC is further segmented into Malaysia, Singapore, Indonesia, Thailand, New Zealand, Vietnam, and Sri Lanka)
• Europe (Germany, UK, France, Spain, Italy, Russia, Rest of Europe; Rest of Europe is further segmented into Belgium, Denmark, Austria, Norway, Sweden, The Netherlands, Poland, Czech Republic, Slovakia, Hungary, and Romania)
• North America (U.S., Canada, and Mexico)
• South America (Brazil, Chile, Argentina, Rest of South America)
• RoW (Saudi Arabia, UAE, South Africa)
For each aforementioned region and country, detailed analysis and data for annual revenue are available for 2015-2026. The breakdown of all regional markets by country and split of key national markets by Synthesis, Manufacturing Process, and Therapeutic Application over the forecast years are also included.
The report also covers current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.
Specifically, potential risks associated with investing in global API market are assayed quantitatively and qualitatively through GMD’s Risk Assessment System. According to the risk analysis and evaluation, Critical Success Factors (CSFs) are generated as a guidance to help investors & stockholders identify emerging opportunities, manage and minimize the risks, develop appropriate business models, and make wise strategies and decisions.
Key Players (this may not be a complete list and extra companies can be added upon request):
AbbVie Inc.
Astrazeneca
Aurobindo Pharma Ltd.
Bayer Healthcare
Bioniche Animal Health
Boehringer Ingelheim
Bristol-Myers Squibb
Ceva Animal Health, Inc.
Elanco Animal Health
Eli Lilly and Company
F. Hoffmann-La Roche
Glaxosmithkline PLC
Heska Co.
Lonza Group
Merck & Co., Inc.
Novartis International AG
Pfizer, Inc.
Ranbaxy Laboratories
Sanofi
Sun Pharmaceutical Industries Ltd.
(Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)

1  Introduction  11
1.1  Industry  Definition  and  Research  Scope  11
1.1.1  Industry  Definition  11
1.1.2  Research  Scope  12
1.2  Research  Methodology  15
1.2.1  Overview  of  Market  Research  Methodology  15
1.2.2  Market  Assumption  16
1.2.3  Secondary  Data  16
1.2.4  Primary  Data  16
1.2.5  Data  Filtration  and  Model  Design  18
1.2.6  Market  Size/Share  Estimation  19
1.2.7  Research  Limitations  20
1.3  Executive  Summary  21
2  Market  Overview  and  Dynamics  23
2.1  Market  Size  and  Forecast  23
2.2  Major  Growth  Drivers  24
2.3  Market  Restraints  and  Challenges  28
2.4  Emerging  Opportunities  and  Market  Trends  31
2.5  Porter’s  Fiver  Forces  Analysis  35
3  Segmentation  of  Global  Market  by  Synthesis  39
3.1  Market  Overview  by  Synthesis  39
3.2  Synthetic  API  41
3.2.1  Branded  Synthetic  API  42
3.2.2  Generic  Synthetic  API  43
3.3  Biotech  API  44
3.3.1  Biotech  API  by  Drug  Type  45
3.3.1.1  Monoclonal  Antibodies  46
3.3.1.2  Recombinant  Proteins  47
3.3.1.3  Vaccines  48
3.3.1.4  Other  Biotech  APIs  49
3.3.2  Biotech  API  by  Customer  Base  50
3.3.2.1  Innovative  Biologic  API  51
3.3.2.2  Generic  Biosimilar  API  52
3.3.3  Biotech  API  by  Expression  Technology  53
3.3.3.1  Mammalian  Expression  54
3.3.3.2  Microbial  Expression  55
3.3.3.3  Yeast  Expression  56
3.3.3.4  Insect  Expression  57
3.3.3.5  Other  Expression  Technologies  58
3.4  HPAPI  59
3.4.1  Branded  HPAPI  60
3.4.2  Generic  HPAPI  61
4  Segmentation  of  Global  Market  by  Manufacturing  Process  62
4.1  Market  Overview  by  Manufacturing  Process  62
4.2  Captive  Manufacturing  64
4.2.1  Branded  Captive  API  65
4.2.2  Generic  Captive  API  66
4.3  Merchant  Manufacturing  67
4.3.1  Merchant  Manufacturing  by  Drug  Type  68
4.3.1.1  Branded  Merchant  API  69
4.3.1.2  Generic  Merchant  API  70
4.3.2  Merchant  Manufacturing  by  Drug  Synthesis  71
4.3.2.1  Merchant  Synthetic  API  72
4.3.2.2  Merchant  Biotech  API  73
5  Segmentation  of  Global  Market  by  Therapeutic  Application  74
5.1  Market  Overview  by  Therapeutic  Application  74
5.2  Infectious  Diseases  76
5.3  Oncology  77
5.4  Ophthalmology  78
5.5  Cardiovascular  Disorders  79
5.6  Central  Nervous  System  80
5.7  Pulmonary  Disorders  81
5.8  Orthopedics  82
5.9  Other  Applications  83
6  Segmentation  of  Global  Market  by  Drug  Type  84
6.1  Market  Overview  by  Drug  Type  84
6.2  Branded  Prescription  Drugs  86
6.3  Generic  Prescription  Drugs  87
6.4  OTC  Drugs  88
7  Segmentation  of  Global  Market  by  Region  89
7.1  Geographic  Market  Overview  2019-2026  89
7.2  North  America  Market  2019-2026  by  Country  95
7.2.1  Overview  of  North  America  Market  95
7.2.2  U.S.  98
7.2.3  Canada  102
7.2.4  Mexico  104
7.3  European  Market  2019-2026  by  Country  106
7.3.1  Overview  of  European  Market  106
7.3.2  UK  109
7.3.3  France  111
7.3.4  Germany  113
7.3.5  Spain  115
7.3.6  Italy  117
7.3.7  Russia  119
7.3.8  Rest  of  European  Market  121
7.4  Asia-Pacific  Market  2019-2026  by  Country  123
7.4.1  Overview  of  Asia-Pacific  Market  123
7.4.2  China  126
7.4.3  Japan  128
7.4.4  India  131
7.4.5  Australia  133
7.4.6  South  Korea  135
7.4.7  Rest  of  APAC  Region  137
7.5  South  America  Market  2019-2026  by  Country  139
7.5.1  Argentina  142
7.5.2  Brazil  144
7.5.3  Chile  146
7.5.4  Rest  of  South  America  Market  148
7.6  Rest  of  World  Market  2019-2026  by  Country  149
7.6.1  UAE  152
7.6.2  Saudi  Arabia  154
7.6.3  South  Africa  156
7.6.4  Other  National  Markets  158
8  Competitive  Landscape  159
8.1  Overview  of  Key  Vendors  159
8.2  New  Product  Launch,  Partnership,  Investment,  and  M&A  162
8.3  Company  Profiles  163
AbbVie  Inc.  163
Astrazeneca  165
Aurobindo  Pharma  Ltd.  166
Bayer  Healthcare  167
Bioniche  Animal  Health  168
Boehringer  Ingelheim  169
Bristol-Myers  Squibb  170
Ceva  Animal  Health,  Inc.  171
Elanco  Animal  Health  172
Eli  Lilly  and  Company  173
F.  Hoffmann-La  Roche  174
Glaxosmithkline  PLC  175
Heska  Co.  176
Lonza  Group  177
Merck  &  Co.,  Inc.  178
Novartis  International  AG  179
Pfizer,  Inc.  180
Ranbaxy  Laboratories  181
Sanofi  182
Sun  Pharmaceutical  Industries  Ltd.  183
9  Investing  in  Global  Market:  Risk  Assessment  and  Management  184
9.1  Risk  Evaluation  of  Global  Market  184
9.2  Critical  Success  Factors  (CSFs)  187
Related  Reports  and  Products  190
Table 1. Snapshot of Global Active Pharmaceutical Ingredients (API) Market, 2019-2026 22
Table 2. Main Product Trends and Market Opportunities in Global Active Pharmaceutical Ingredients (API) Market 31
Table 3. Global Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 39
Table 4. Global Active Pharmaceutical Ingredients (API) Market: Synthetic API by Drug Type, 2015-2026, $ bn 41
Table 5. Global Active Pharmaceutical Ingredients (API) Market: Biotech API by Drug Type, 2015-2026, $ bn 45
Table 6. Global Active Pharmaceutical Ingredients (API) Market: Biotech API by Customer Base, 2015-2026, $ bn 50
Table 7. Global Active Pharmaceutical Ingredients (API) Market: Biotech API by Expression Technology, 2015-2026, $ bn 53
Table 8. Global Active Pharmaceutical Ingredients (API) Market: HPAPI by Drug Type, 2015-2026, $ bn 59
Table 9. Global Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 62
Table 10. Global Active Pharmaceutical Ingredients (API) Market: Captive Manufacturing by Drug Type, 2015-2026, $ bn 64
Table 11. Global Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Type, 2015-2026, $ bn 68
Table 12. Global Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Synthesis, 2015-2026, $ bn 71
Table 13. Global Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 74
Table 14. Global Active Pharmaceutical Ingredients (API) Market by Drug Type, 2015-2026, $ bn 84
Table 15. Global Active Pharmaceutical Ingredients (API) Market by Region, 2015-2026, $ bn 90
Table 16. Total Health Expenditure per capita in PPP International U.S. Dollars by Country 92
Table 17. Leading National Active Pharmaceutical Ingredients (API) Market, 2019 and 2026, $ bn 94
Table 18. North America Active Pharmaceutical Ingredients (API) Market by Country, 2015-2026, $ bn 97
Table 19. U.S. Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 100
Table 20. U.S. Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 100
Table 21. U.S. Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 100
Table 22. Canada Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 103
Table 23. Canada Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 103
Table 24. Canada Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 103
Table 25. Mexico Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 105
Table 26. Mexico Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 105
Table 27. Mexico Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 105
Table 28. Europe Active Pharmaceutical Ingredients (API) Market by Country, 2015-2026, $ bn 108
Table 29. UK Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 110
Table 30. UK Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 110
Table 31. UK Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 110
Table 32. France Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 112
Table 33. France Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 112
Table 34. France Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 112
Table 35. Germany Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 114
Table 36. Germany Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 114
Table 37. Germany Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 114
Table 38. Spain Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 116
Table 39. Spain Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 116
Table 40. Spain Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 116
Table 41. Italy Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 118
Table 42. Italy Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 118
Table 43. Italy Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 118
Table 44. Russia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 120
Table 45. Russia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 120
Table 46. Russia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 120
Table 47. Active Pharmaceutical Ingredients (API) Market in Rest of Europe by Country, 2015-2026, $ bn 122
Table 48. APAC Active Pharmaceutical Ingredients (API) Market by Country, 2015-2026, $ bn 125
Table 49. China Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 127
Table 50. China Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 127
Table 51. China Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 127
Table 52. Japan Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 130
Table 53. Japan Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 130
Table 54. Japan Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 130
Table 55. India Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 132
Table 56. India Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 132
Table 57. India Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 132
Table 58. Australia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 134
Table 59. Australia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 134
Table 60. Australia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 134
Table 61. South Korea Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 136
Table 62. South Korea Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 136
Table 63. South Korea Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 136
Table 64. Active Pharmaceutical Ingredients (API) Market in Rest of APAC by Country, 2015-2026, $ bn 138
Table 65. South America Active Pharmaceutical Ingredients (API) Market by Country, 2015-2026, $ bn 141
Table 66. Argentina Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 143
Table 67. Argentina Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 143
Table 68. Argentina Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 143
Table 69. Brazil Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 145
Table 70. Brazil Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 145
Table 71. Brazil Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 145
Table 72. Chile Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 147
Table 73. Chile Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 147
Table 74. Chile Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 147
Table 75. RoW Active Pharmaceutical Ingredients (API) Market by Country, 2015-2026, $ bn 151
Table 76. UAE Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 153
Table 77. UAE Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 153
Table 78. UAE Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 153
Table 79. Saudi Arabia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 155
Table 80. Saudi Arabia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 155
Table 81. Saudi Arabia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 155
Table 82. South Africa Active Pharmaceutical Ingredients (API) Market by Synthesis, 2015-2026, $ bn 157
Table 83. South Africa Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2015-2026, $ bn 157
Table 84. South Africa Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2015-2026, $ bn 157
Table 85. AbbVie Inc.: Company Snapshot 163
Table 86. AbbVie Inc.: Business Segmentation 163
Table 87. AbbVie Inc.: Product Portfolio 164
Table 88. AbbVie Inc.: Revenue, 2016-2018, $ bn 164
Table 89. AbbVie Inc.: Recent Developments 164
Table 90. Risk Evaluation for Investing in Global Market, 2019-2026 185
Table 91. Critical Success Factors and Key Takeaways 188
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